Quantitative autistic traits ascertained in a national survey of 22 529 J apanese schoolchildren
نویسندگان
چکیده
منابع مشابه
Quantitative autistic traits ascertained in a national survey of 22 529 Japanese schoolchildren
OBJECTIVE Recent epidemiologic studies worldwide have documented a rise in prevalence rates for autism spectrum disorders (ASD). Broadening of diagnostic criteria for ASD may be a major contributor to the rise in prevalence, particularly if superimposed on an underlying continuous distribution of autistic traits. This study sought to determine the nature of the population distribution of autist...
متن کاملMapping quantitative traits with random and with ascertained sibships.
Use of a robust score statistic based on a variance components model to map quantitative trait loci in randomly sampled pedigrees is reviewed. Sibships ascertained through a single proband are discussed. Under a standard assumption of multivariate normality, two suggested methods of ascertainment correction are shown to be asymptotically equivalent when the number of sibships is large.
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ژورنال
عنوان ژورنال: Acta Psychiatrica Scandinavica
سال: 2012
ISSN: 0001-690X,1600-0447
DOI: 10.1111/acps.12034